Adenocarcinoma is a type of cancer that arises from the endothelial cells of glandular structures. Adenocarcinoma is the most common type of cancer to occur in the PROSTATE GLAND (PROSTATE CANCER), gastrointestinal tract (ESOPHAGEAL CANCER, STOMACH CANCER, PANCREATIC CANCER, LIVER CANCER, COLORECTAL CANCER), and endocrine glands (TESTICULAR CANCER, OVARIAN CANCER, THYROID CANCER). Adenocarcinoma begins as a benign (noncancerous) tumor, an adenoma. Over
The changes that take place in an ADENOMA, a benign (noncancerous) tumor, as it transforms into an ADENOCARCINOMA, a malignant (cancerous) tumor. The transition to cancer can occur with any adenoma though is most common with adenomas of the colon (intestinal polyps, also called adenomatous polyps). Only a small percentage of adenomas become cancerous. The sequence of events that transform an adenoma to an adenocarcinoma begins with multiple mutations in
The current generation of adults is the first to grow up in the era of successful treatment for many childhood cancers. Nearly 300,000 American adults who are now in their 20s, 30s, and 40s enjoy CANCER-free, healthy lives. Doctors consider treatments for most types of LEUKEMIA, the most common childhood cancer, to be curative. Treatments for many types of BONE CANCER, BRAIN cancer, Hodgkin’s LYMPHOMA, and kidney cancer (WILMS’S TUMOR) are
Therapies outside the realm of conventional medical methods that are promoted to relieve cancer symptoms. Alternative practices are used instead of conventional treatments and methods; complementary practices are used in conjunction with conventional treatments and methods. Some therapies and remedies may be either alternative or complementary, depending on how they are used. Because some cancer treatment protocols are very precise, it is important to
Substances that stop tumors from developing new BLOOD vessels to support their survival. Numerous proteins and enzymes in the body function to encourage or suppress the growth of new blood vessels. Cancerous tumors are among the tissues that produce proteins that foster new blood vessel growth; these blood vessels then deliver to the tumor the nourishment it needs to grow. Cutting off the blood supply starves the tumor, causing its cells to die.
A cancerous tumor that arises from the immature cells that form the basis for an organ’s structure. The cells are undifferentiated, which means they have not yet developed a specific role within the body. Researchers believe these are embryonic cells. Blastomas grow as the type of tissue where the embryonic cells remain after organ development. Blastomas nearly always occur in childhood, though occasionally may occur in early adulthood. Most
BREAST CANCER GENE 1 and breast cancer gene 2, the first genes in which researchers identified mutations that correlate to increased susceptibility to BREAST cancer and OVARIAN CANCER. About one in six women who have either of these cancers have mutations in either or both of the genes. Many are women who have a known family history of breast cancer or ovarian cancer. The presence of mutations in either of these genes means a woman has an increased risk
Cancer ANTIGEN 125, a protein often elevated in the BLOOD circulation when certain cancers are growing in the body. The cells of the OVARIES, UTERUS, and FALLOPIAN TUBES produce CA-125; consequently CA-125 levels rise in OVARIAN CANCER, ENDOMETRIAL CANCER (cancer of the uterus), and CERVICAL CANCER. The most pronounced elevation occurs with ovarian cancer. However, numerous factors other than cancer can produce elevated CA-125 levels, including benign